Laboratory Surfactants and Wetting Agents
Medchemexpress LLC Polyoxyethylene stearyl ether | 9005-00-9 | MFCD00074177 | 99.0% | ≈1,100 g/mol | (C2H4O)nC18H38O | 25 G
Polyoxyethylene (20) stearyl ether is an ethoxylated stearyl alcohol (PEG-20 stearyl ether) nonionic surfactant used as a PEGylated lipid excipient for formulation research. It is commonly employed to form and stabilize nanoparticles and liposomal systems; the material is typically a colorless to off-white oil with CAS 9005-00-9.
- Acts as a nonionic PEGylated lipid surfactant for nanoparticle and liposome formulation.
- Provides steric stabilization and improves colloidal stability.
- Soluble in ethanol at approximately 100 mg/mL with ultrasonic assistance.
- Colorless to off-white oil, suitable for formulation studies.
- Average ethoxylation degree approximately n ≈ 20; number-average molecular weight ~1,100 g/mol.
eMolecules 511-26-2 | Medchem Express | MAP4343 | 5mg | 572596436 | HY-107116 | 330.512 | C22H34O2
Medchem Express | MAP4343 | 5mg | 572596436 | HY-107116 | 511-26-2 | 330.512 | C22H34O2
Cambridge Isotope Laboratories TAUROCHOLIC ACID, SODIUM SALT HYDRATE UNLABELED 97% CHEMICAL PURITY, 50 MG
TAUROCHOLIC ACID, SODIUM SALT HYDRATE UNLABELED 97% CHEMICAL PURITY, 50 MG
Medchemexpress LLC Methanone, [(2S,3aS,7aS)-octahydro-1-[[(1R,2R)-2-phenylcyclopropyl]carbonyl]-1H-indol-2-yl]-3-thiazolidinyl- | 176797-26-5 | C22H28N2O2S | 50 MG
S 17092 (S 17092-1) is an orally active cerebral prolyl-endopeptidase (PEP) inhibitor with an IC50 of 1.2 nM. It inhibits cell apoptosis by slowing down the degradation of neuroactive peptides, thereby enhancing memory function. It is suitable for research on memory impairment and cognitive disorders associated with cerebral aging.
- Orally active cerebral prolyl-endopeptidase (PEP) inhibitor
- Inhibits cell apoptosis
- Enhances memory function
- Useful for research on memory impairment and cognitive disorders
- Long-acting PEP inhibitor with a half-life of over 9 hours
Medchemexpress LLC Cid44216842 (Cdc42-IN-1) | 1222513-26-9 | 99.8% | C22H20BrN3O3S | 10MG
CID44216842 (Cdc42-IN-1) is a potent, selective small-molecule inhibitor of the Rho GTPase Cdc42 that blocks GTP and GDP binding to both wild-type and Q61L mutant forms. Supplied as a solid white to off-white powder with high purity, it is intended for use as a molecular probe in biochemical and cellular research.
- Selective inhibition of Cdc42 over other GTPases.
- Low-micromolar potency in GTP and GDP binding assays.
- High chemical purity suitable for research applications.
- Stable solid form with defined storage conditions.
- Useful as a molecular probe for studying Cdc42-mediated signaling.
Medchemexpress LLC Serpin A8/Angiotensi 500ug
Serpin A8 (or angiotensinogen) is an important regulator in the renin-angiotensin system fine-tuning blood pressure and electrolyte balance This multifunctional protein acts as a potent vasoconstrictor affecting vascular smooth muscle and affecting cardiac function via the sympathetic nervous system Serpin A8/Angiotensinogen Protein Mouse (HEK293 His) is the recombinant mouse-derived Serpin A8/Angiotensinogen protein expressed by HEK293 with C-His labeled tag
eMolecules 26530-26-7 | Medchem Express | KM04416 | 5mg | 779715174 | HY-148685 | MFCD00097921 | 249.28 | C12H11NO3S
Ambeed | (E)-4455-Tetramethyl-2-(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-en-1-yl)-132-dioxaborolane | 250mg | 660584824 | A630869 | 642066-70-4 | 268.160 | C14H25BO4
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Medchemexpress LLC Cdc42-IN-1 | 1222513-26-9 | 99.8% | 486.38 | 50 MG
CID44216842 (Cdc42-IN-1) is a potent and selective guanine nucleotide binding lead inhibitor targeting Cdc42. It functions as a molecular probe, specifically inhibiting GTP binding to both Cdc42 and its mutant in a dose-dependent manner. This inhibition is specific toward Cdc42 with no effects on other GTPases including Rac and Rho in the same family.
- Potent Cdc42-selective guanine nucleotide binding lead inhibitor
- EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay
- EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay
- Used as a molecular probe
- Specific inhibition of Cdc42 without affecting other GTPases like Rac and Rho
Medchemexpress LLC CC260 | 2411088-26-9 | 99.5% | 490.43 | 50 MG
CC260 is a selective PI5P4Kα and PI5P4Kβ inhibitor with Kis of 40 nM and 30 nM, respectively. It does not inhibit or weakly inhibits other protein kinases, such as Plk1 and RSK2. This compound can be used for cell energy metabolism, diabetes and cancer research.
- Enhances Insulin-induced Akt phosphorylation
- Suppresses S6K phosphorylation by mTORC1
- Significantly increases phosphorylation of acetyl-CoA carboxylase (ACC)
- Reduces ability of cells to survive serum starvation
- Causes an increase in glycolytic ATP production
- Useful for cell energy metabolism, diabetes and cancer research
Medchemexpress LLC Epoy (SD-142) | 245660-13-3 | 98.8% | 323.30 | 5 MG
EpoY (SD-142) is an irreversible inhibitor of the brain's primary tubulin tyrosine carboxypeptidase (TCP), a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP). It inhibits TCP with an IC50 value of approximately 500 nM, leading to a decrease in detyrosinated alpha-tubulin levels, which is vital for microtubule dynamics and neuronal differentiation. This inhibition results in significant differentiation defects and has been linked to issues associated with cancer and cardiomyopathies.
- Irreversible inhibitor of tubulin tyrosine carboxypeptidase (TCP)
- Inhibits TCP with an IC50 value of approximately 500 nM
- Decreases levels of detyrosinated alpha-tubulin
- Crucial for microtubule dynamics and neuronal differentiation
- Linked to issues associated with cancer and cardiomyopathies
- For research use only
Medchemexpress LLC Serpin A8/Angiotensi 10ug
Serpin A8 (or angiotensinogen) is a key regulator of the renin-angiotensin system affecting blood pressure fluid and electrolyte balance As a vasoconstrictor it directly affects vascular smooth muscle and affects myocardial contractility and heart rate through the sympathetic nervous system Serpin A8/Angiotensinogen Protein Rat (HEK293 His) is the recombinant rat-derived Serpin A8/Angiotensinogen protein expressed by HEK293 with C-His labeled tag
eMolecules 955413-26-0 | 6-(Trifluoromethyl)quinolin-8-amine | ChemScene | MFCD22627929 | 212.175 | C10H7F3N2 | 98.000 | Nc1cc(cc2cccnc12)C(F)(F)F | 100mg | 687357874
6-(Trifluoromethyl)quinolin-8-amine | ChemScene | 955413-26-0 | MFCD22627929 | 212.175 | C10H7F3N2 | 98.000 | Nc1cc(cc2cccnc12)C(F)(F)F | 100mg | 687357874